I told you that I found arguments in everything I wrote! and it is some good points raised.
Here is my take.
Greg,
Yes,
But only in the exact context of my initial wording. "In General" and Harmonic frequency" not crank design etc, The design obviously has a much higher importance than the mass (within limits) but yes, you have a good example with the 750SF Frame!
With a lighter re designed crank (again in general) you lower the forces on your bearings etc and are changing far more than just the mass so it is hard to compare one to the other directly. Harmonic balancers, (big chunks of metal designed to "capture" unwanted harmonics)
Of course the heavier crank will generate larger loads, and depending on what the loads are being applied to etc you either will or will not notice!
I can though give you a very relevant example.
We specialise in Pre-war Lagondas and one of the engines is a 4.5 litre 6 in line.
This engine has a definite "period" at 2300 to 2600 where it is so noticeable on some engines that you dare not stay there!
It has a front balancer and if you remove this, the crank will surely break! and does regularly!
The standard forged crank is a fairly light affair but not badly designed for the period, We change this for a Heavier later crank but of similar design, Problem solved until you go racing and get other problems!
Then we change it again for a modern design crank that is actually still heavier due to correctly designed counterweights etc and you never see any problem again! Although this latter crank is not really relevant to the "mass" discussion as it is of far better design.
Another example is engines I used to build for F1 Ski racing, these were 8.2 litre twin turbo Big Block Chevy full race engines revving up to 8000 rpm! and some races were full throttle flat out for 1 hour. If we used the US made light weight cranks in the full power "Flat water" race engines we would regularly snap a crank during test simulations on the dyno! When changed to heavier cranks from the same manufacturer and of very similar design, we had no problems!
So my experience with this and many many other cranks etc has been one of mass helping disperse unwanted harmonics but as I say, strictly on an "all other things being equal" foot note!
Also read up on NASCAR engines, these too use lighter cranks for the "sprint" and small oval races and heavier cranks for the longer full power speedways! for exactly the same reasons.
Cam,
I know what you are saying and have the same smoke emitting from my head as you do.
However. to "Simplify" this equation, is to get it wrong!
We all know that theories that say one thing when the practice shows otherwise are Unarguably Wrong.
That means to say, "something is missing from the equation"
Now I have thought long and hard for many years on this and added this and that theory etc and have listened and read this person's and that person's work etc and tried to include what I thought was ans was not relevant and each time I have made my own arguments for and against my own theories.
Trouble is when we try to theorise that something that "IS" happening should not happen! and can not happen! We must be missing something, and unfortunately "I" don't know what, I just know that "we are"
If we take the vertical twin 270/450 frank firing order, "In theory" this should be crap! in practice it works well, In other theories it is not optimal, but close! In others "Rocking couple" should not exist! But it does!! There is far too much to this equation for us to just "Theorise" without testing and using many years of practical experimentation!
I am not for one minute saying that we do not need theories, just that we really "DO" need experimentation! and then try to work out what part of our theories applies to our practice. Trouble is that experimentation is expensive in both time and money, and not many of us have either let alone both!

And those that do, "The manufacturers" regularly get it wrong! so what chance have thickos like me got?
Julian, needing coffee fast!